1001 SE Morrison St., 239-7639, holocene.org. 8:30 pm-late Wednesday-Thursday and Saturday, 5 pm-late Friday, hours vary Sunday-Tuesday.

As far as clubs go, Holocene is the incumbent champion, if only recently so. Cult Chicago DJs, the raucous meat market of Booty Bassment and local indie folksters have all shared the sprawling eastside warehouse space in its decade of existence. A seasonal cocktail program is anchored by the evergreen—and well-balanced—Ginger Rogers and cucumber-happy Town and Country gin and tonic (both $7). Beyond cocktails and rotating slush specials, bottled beer and wine options abound by the dozen. The best time for casual sipping is the weekly Friday happy hour, where the lighting is up and the DJs down. For a spot that exudes medical-grade cool, the service and staff are welcoming and speedy, even on the steamiest club nights.

Happy hour: 5-8 pm Friday. Food and drink specials vary—think kale and Hungarian sausage.
Entertainment: Hip DJs and bands of all stripes perform nightly.